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Generally, phentermine appears to be relatively well
tolerated.[3] It can produce side effects consistent
with its catecholamine-releasing properties, e.g., tachycardia
(increased heart rate) and elevated blood pressure,
but the incidence and magnitude of these appear to be
less than with the amphetamines. Because phentermine
acts through sympathomimetic pathways, the drug may
increase blood pressure and heart rate. It may also
cause palpitations, restlessness, and insomnia. Additionally,
phentermine has the potential to cause physical and
psychological dependence.
- Insomnia
- Increased blood pressure
- Irritability
- Nervousness
- Sense of well-being
- Blurred vision
- Change in sexual desire
- Clumsiness
- Confusion
- Diarrhea
- Dizziness
- Dry mouth
- Headache
- Irregular heartbeat
- Nausea or vomiting
- Psychosis
- Skin rash or itching
- Stomach pain
- Tiredness
- Unpleasant taste
- Possible Overdose Symptoms
- Confusion
- Convulsions (seizures)
- Dizziness
- Fast Breathing
- Fever
- Hallucinations
- Hostility with urge to attack
- Irregular blood pressure
- Irregular heartbeat
- Lightheadedness or Fainting
- Mental Depression, following a period of excitement
- Tremors, Trembling, or Shaking
- Overactive Reflexes
- Panic
- Restlessness
- Severe nausea, vomiting or diarrhea
- Stomach cramps
- Tiredness or Weakness
Patients with the following should not use Phentermine:
- An allergy to any ingredient in Phentermine or
other sympathomimetics (eg, pseudoephedrine)
- Are also taking dexfenfluramine, fenfluramine,
furazolidone, guanadrel, guanethidine, or have taken
a monoamine oxidase inhibitor (MAOI) (eg, phenelzine)
in the last 14 days
- Have severe high blood pressure, an overactive
thyroid, glaucoma, heart or blood vessel disease,
or severe narrowing of the blood vessels
- Are in an agitated state, or have a history of
substance abuse
Some medical conditions may interact with
Phentermine, patients with the following should consult
with their doctor before using phentermine:
- Are pregnant, planning to become pregnant, or are
breast-feeding
- Are taking any prescription or nonprescription
medicine, herbal preparation, or dietary supplement
- Have allergies to medicines, foods, or other substances
- Have a brain or spinal cord disorder, hardening
of the arteries, high blood pressure, diabetes, or
high cholesterol or lipid levels
Some medicines may interact with Phentermine,
such as the following:
- Dexfenfluramine, fenfluramine, furazolidone, or
MAOIs (eg, phenelzine) because the risk of serious
side effects, such as increasing headache, high blood
pressure, slow heart rate, elevated temperature, or
possibly fatal lung problems, may be increased
- Serotonin specific reuptake inhibitors (eg, fluoxetine)
because the risk of their side effects may be increased
by Phentermine
- Guanadrel or guanethidine because their effectiveness
may be decreased by Phentermine
External Links
Medline
Plus / About Phentermine
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